News
Who will pay my pension someday...?
Information event on pension rights for Internationally Mobile Researchers.
PhD Funding through the TUM Graduate School
STIBET Program of the DAAD // Internationalization voucher of the TUM-GS
Biomedical Applications for Cancer Treatment
April 23rd, 2015 I 04.00-06.00pm I Klinikum rechts der Isar I Pavillon Lecture Hall
Events
Christian Hundshammer, M.Sc.
Member of GSISH
Contact Details
Clinic and Polyclinic for Nuclear Medicine
Klinikum rechts der Isar
TU München
Ismaningerstr. 22
81675 München
Germany
Phone: +49 (0)89.4140.7722
E-Mail: christian.hundshammer(at)tum.de
Project Details
Project:
Multinuclear NMR-Spectroscopy applied on a PET/MR System
Supervisors:
Prof. Dr. Steffen Glaser
Prof. Dr. Axel Haase
Prof. Dr. Markus Schwaiger
Start of PhD-work at GSISH:
July 2014
Project Description:
Metabolic data of cells and tissues provide detailed information about their physiological state and can therefore help to detect diseases and monitor their therapy. Cancer, ischemia, and neurodegenerative disorders cause significant changes of the extra- and intracellular environment, altering the glucose metabolism, the sodium balance, energy levels, and the pH.
Magnetic resonance imaging (MRI) is a non-invasive technique with strong potential to visualize disease-associated metabolic changes in the clinics. Embedded in the “Sonderforschungsbereich” 824, this project aims to apply multinuclear NMR spectroscopy on a 3 T PET/MRI system. Besides sodium-23 and phosphorus-31 spectroscopy, this thesis will focus on in vivo and in vitro measurements with carbon-13 compounds since they can be used to sense metabolic processes and alterations of the pH. To overcome one main drawback of MRI- the small sensitivity of metabolically relevant molecules- dynamic nuclear polarization (DNP) protocols should be established and applied simultaneously.
Publications:
Poster:
Duewel Stephan, Malte Gersch, Benedikt Feuerecker, Hundshammer Christian, Markus Schwaiger, Steffen Glaser, Franz Schilling.
A Novel pH-Biosensor for Magnetic Resonance Imaging and Spectroscopy.
COST DNP school on hyperpolarization techniques. Marseille.
Talks:
Hundshammer Christian, Duewel Stephan, Malte Gersch, Benedikt Feuerecker, Markus Schwaiger, Steffen Glaser, Franz Schilling.
A Novel pH-Biosensor for Magnetic Resonance Imaging.
COST DNP school on hyperpolarization techniques. Marseille.
Personal Details:
For Curriculum Vitae of Christian Hundshammer please click here.