Associated member of GSISH

Contact Details

Department of Nuclear Medicine
Klinikum Rechts der Isar
TU München
Ismaninger Str. 22
81675 München

Phone: +49 (0)89.4140.6397

E-Mail: rebekka.loeb@lrz.tu-muenchen.de

Project Details

Project:
Dynamic Reconstruction from Simultaneously Acquired PET/MR Data

Supervisors:
Prof. Dr. Sibylle Ziegler
Prof. Dr. Axel Haase

Start of PhD-work at GSISH:
November 2010

Project Description:
In recent years the combination of Positron-Emission-Tomography (PET) and Magnetic Resonance (MR) imaging has gained increased interest. Among the unprecedented opportunities provided by integrated PET/MR scanners are an excellent spatial alignment of both modalities and practically simultaneous data acquisition. The Munich HYCON (Munich HYbrid imaging CONsortium) is currently installing one of the first fully-integrated whole-body PET/MR scanner in the Nuclear-Medicine Department at the Klinikum rechts der Isar. The aim of this project is to develop new image generation algorithms that make use of such novel integrated devices. A special focus will be their evaluation on clinically relevant data. It is proposed for the first time to incorporate MR-based anatomical information in order to improve the quality of four-dimensional (4D) PET reconstruction, both of radiotracer uptake and of physiological kinetic parameters.

Publications:

R.Kraus, G. Delso, S. I. Ziegler,
"Simulation Study of Tissue-Specific Positron Range Correction for the New Biograph mMR Whole-Body PET/MR System",
IEEE Trans. Nucl. Sci, 2012, 59, 1900-1909

R. Kraus, G. Delso, S. Ziegler,
"Fully 4D image reconstruction of simultaneously acquired PET/MR data for [18F]FET,"
in Journal of Nuclear Medicine, Proceedings of Annual Meeting of Society of Nuclear Medicine (SNM 2012), vol. 53, no. Suppl. 1, Miami (FL), USA, June 2012

R. Kraus, G. Delso, S. Ziegler,
"3D reconstruction with an extended system model for the new Biograph mMR whole-body MR/PET system,"
in Journal of Nuclear Medicine, Proceedings of Annual Meeting of Society of Nuclear Medicine (SNM 2011), vol. 52, no. Suppl. 1, San Antonio (TX), USA, June 2011

G. Delso, R. Kraus, A. Martinez-Moeller, R. A. Bundschuh, S. G. Nekolla, S. I. Ziegler
"Correction of Truncation Artifacts in Simultaneous Whole-Body PET/MR with an Active Model of the Patient Arms"
IEEE NSS/MIC, Nov 2010

R. Kraus, G. Delso, H.-P. Loeb, A. Martinez-Möller, R. Bundschuh, A. Drzezga, S. Ziegler
"An inpainting approach for the correction of incomplete attenuation maps in PET/MR"
Journal of Nuclear Medicine, Proceedings of Annual Meeting of Society of Nuclear Medicine (SNM 2010), vol. 51, no. Suppl. 2, Salt Lake City, USA, June 2010, p. 1380

G. Delso, R. Kraus, R. Bundschuh, A. Martinez-Möller, S. Nekolla, S. Ziegler
"PET/MR truncation artifact reduction with an active model of the patient’s arms"
Journal of Nuclear Medicine, Proceedings of Annual Meeting of Society of Nuclear Medicine (SNM 2010), vol. 51, no. Suppl. 2, Salt Lake City, USA, June 2010, p. 1379

Personal Details:

09/2009 - present:
Research assistant at the Nuclear Medicine Department of the Klinikum Rechts der Isar (TUM)

10/2002 - 03/2009:
Study of Mathematics at the TU Karlsruhe
Minor field of study: Biomedical Engineering
Specialization: Signal Analysis, Inverse Problems, Optimization Theory, Compressed Sensing

12/2006 - 03/2007:
Internship with Siemens AG
Main task: Object-oriented design and implementation of a graphical tool for font capturing using Microsoft Visual Studio and C++